Assay Detail

CHEMBL3293297

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Binding

Displacement of [3H]-CP-55,940 from CB2 receptor (unknown origin)

ChEMBL ↗

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Target

Cannabinoid receptor 2 (CHEMBL253) ↗

Open DB target context

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Primary target Cannabinoid receptor 2

CHEMBL253

Anchored from Assay target.

Protein identity Cannabinoid receptor 2

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

Cannabinoid receptor 2 (CHEMBL253) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Tricyclic pyrazoles. Part 6. Benzofuro[3,2-c]pyrazole: a versatile architecture for CB2 selective ligands.

Pinna G, Loriga G, Lazzari P, Ruiu S, Falzoi M, Frau S, Pau A, Murineddu G, Asproni B, Pinna GA.
Eur J Med Chem (2014) 82 : 281 -292
PubMed 24922543 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Ki	1	9.55	9.55

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL381689	SR-144528	—	1	9.55

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL381689	SR-144528	Ki	=	0.28	nM	9.55