Assay Detail
Binding
CHEMBL3293671
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Displacement of [3H]-CP-55940 from human CB2 receptor expressed in HEK293T cell membranes by scintillation counting
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK-293T |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Ultrapure ajulemic acid has improved CB2 selectivity with reduced CB1 activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.13 | 8.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL111 | RIMONABANT | 4.0 | 1 | 8.96 |
| CHEMBL3290053 | — | — | 1 | 7.29 |
| CHEMBL381689 | SR-144528 | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL111 | RIMONABANT | Ki | = | 1.1 | nM | 8.96 |
| CHEMBL3290053 | — | Ki | = | 51.0 | nM | 7.29 |
| CHEMBL381689 | SR-144528 | Ki | - | — | - |