Assay Detail
Binding
CHEMBL3294893
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at beta2 receptor in guinea pig trachea assessed as fast onset of inhibition of electrically stimulated contraction
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Tissue | Trachea |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Multivalent design of long-acting β(2)-adrenoceptor agonists incorporating biarylamines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 9.55 | 10.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1940832 | MILVETEROL | 2.0 | 1 | 10.30 |
| CHEMBL1256786 | FORMOTEROL | 4.0 | 1 | 8.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1940832 | MILVETEROL | EC50 | = | 0.05012 | nM | 10.30 |
| CHEMBL1256786 | FORMOTEROL | EC50 | = | 1.585 | nM | 8.80 |