Beta-2 adrenergic receptor · SINGLE PROTEIN · Cavia porcellus
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As of 2026-09-14Protein identity stays anchored to UniProt Q8K4Z4. Use UniProt Q8K4Z4 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8K4Z4 as the stable identity anchor, then attach disease evidence before program review.
Beta-2 adrenergic receptor
Review this target as Beta-2 adrenergic receptor, mapped to UniProt Q8K4Z4. Sequence length is 418 aa.
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This review treats Beta-2 adrenergic receptor as ChEMBL target CHEMBL5414, mapped to UniProt Q8K4Z4. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Beta-2 adrenergic receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Cavia porcellus |
| UniProt | Q8K4Z4 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Beta-2 adrenergic receptor |
| UniProt Accession | Q8K4Z4 |
| Component Type | Protein |
| Sequence Length | 418 aa |
Beta-2 adrenergic receptor
Review this target as Beta-2 adrenergic receptor, mapped to UniProt Q8K4Z4. Sequence length is 418 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5557828 | 10.9 | IC50 | 0.01259 | Preclinical |
| CHEMBL5505816 | 10.6 | IC50 | 0.02512 | Preclinical |
| CHEMBL1682213 | 10.3 | EC50 | 0.05 | Preclinical |
| CHEMBL1940832 | 10.3 | EC50 | 0.05012 | Clinical |
| CHEMBL5208201 | 10.3 | IC50 | 0.05012 | Preclinical |
| CHEMBL6067687 | 10.3 | IC50 | 0.05012 | Preclinical |
| CHEMBL304344 | 10.2 | Kd | 0.0631 | Preclinical |
| CHEMBL1682210 | 10.15 | EC50 | 0.07 | Preclinical |
| CHEMBL552398 | 10.14 | EC50 | 0.072 | Preclinical |
| CHEMBL5172865 | 10.1 | IC50 | 0.07943 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 89 | 194 | 6.6 |
| tissue-based format | 13 | 53 | 6.6 |
| cell membrane format | 2 | 4 | 7.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 45 | 140 | 8.0 |
| assay format | 33 | 46 | 7.0 |