Assay Detail
Functional
CHEMBL3295667
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at human recombinant at D1 receptor assessed as inhibition of dopamine-induced cAMP accumulation
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel arylsulfonamide derivatives with 5-HT₆/5-HT₇ receptor antagonism targeting behavioral and psychological symptoms of dementia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kb | 1 | - | - |
| IC50 | 1 | 8.77 | 8.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1814790 | — | — | 1 | 8.77 |
| CHEMBL3290012 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1814790 | — | IC50 | = | 1.7 | nM | 8.77 |
| CHEMBL3290012 | — | Kb | = | 37.0 | nM | - |