Assay Detail
ADMET
CHEMBL3296504
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Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay
6
Total Activities
5
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | WI-38 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and in vitro antiproliferative evaluation of novel N-alkylated 6-isobutyl- and propyl pyrimidine derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.29 | 6.52 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3288102 | — | — | 2 | 6.52 |
| CHEMBL1835794 | — | — | 1 | 5.42 |
| CHEMBL3288101 | — | — | 1 | 4.71 |
| CHEMBL3288100 | — | — | 1 | 4.51 |
| CHEMBL3288099 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3288102 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL1835794 | — | IC50 | = | 3800.0 | nM | 5.42 |
| CHEMBL3288101 | — | IC50 | = | 19400.0 | nM | 4.71 |
| CHEMBL3288100 | — | IC50 | = | 30800.0 | nM | 4.51 |
| CHEMBL3288102 | — | Activity | - | — | - | |
| CHEMBL3288099 | — | IC50 | - | — | - |