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Assay Detail

CHEMBL3299305

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of CDK2/cyclin A (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 7 — Homologous single protein target
Curated By Autocuration

Target

CDK2/Cyclin A2 (CHEMBL3038469)
Type PROTEIN COMPLEX
Organism Homo sapiens

Publication

Acridone alkaloids from Glycosmis chlorosperma as DYRK1A inhibitors.
Beniddir MA, Le Borgne E, Iorga BI, Loaëc N, Lozach O, Meijer L, Awang K, Litaudon M.
J Nat Prod (2014) 77 : 1117 -1122
PubMed 24798019 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.09 5.09

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3297832 1 5.09

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3297832 IC50 = 8200.0 nM 5.09