Assay Detail
Functional
CHEMBL3362072
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Cytotoxicity against human WI38 cells after 24 hrs by SRB assay
18
Total Activities
18
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | WI-38 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis of novel 1,2,4-triazoles, triazolothiadiazines and triazolothiadiazoles as potential anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 18 | 6.02 | 6.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3329557 | — | — | 1 | 6.32 |
| CHEMBL3329550 | — | — | 1 | 6.19 |
| CHEMBL3329554 | — | — | 1 | 5.89 |
| CHEMBL3329551 | — | — | 1 | 5.66 |
| CHEMBL3329548 | — | — | 1 | - |
| CHEMBL1209368 | — | — | 1 | - |
| CHEMBL1209369 | — | — | 1 | - |
| CHEMBL1980095 | — | — | 1 | - |
| CHEMBL1209370 | — | — | 1 | - |
| CHEMBL1460271 | — | — | 1 | - |
| CHEMBL3329549 | — | — | 1 | - |
| CHEMBL3329552 | — | — | 1 | - |
| CHEMBL3329553 | — | — | 1 | - |
| CHEMBL3329555 | — | — | 1 | - |
| CHEMBL3329556 | — | — | 1 | - |
| CHEMBL3329558 | — | — | 1 | - |
| CHEMBL3329547 | — | — | 1 | - |
| CHEMBL17289 | CHS-828 | 1.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3329557 | — | IC50 | = | 480.0 | nM | 6.32 |
| CHEMBL3329550 | — | IC50 | = | 650.0 | nM | 6.19 |
| CHEMBL3329554 | — | IC50 | = | 1288.0 | nM | 5.89 |
| CHEMBL3329551 | — | IC50 | = | 2189.0 | nM | 5.66 |
| CHEMBL3329548 | — | IC50 | - | — | - | |
| CHEMBL1209368 | — | IC50 | - | — | - | |
| CHEMBL1209369 | — | IC50 | - | — | - | |
| CHEMBL1980095 | — | IC50 | - | — | - | |
| CHEMBL1209370 | — | IC50 | - | — | - | |
| CHEMBL1460271 | — | IC50 | - | — | - | |
| CHEMBL3329549 | — | IC50 | - | — | - | |
| CHEMBL3329552 | — | IC50 | - | — | - | |
| CHEMBL3329553 | — | IC50 | - | — | - | |
| CHEMBL3329555 | — | IC50 | - | — | - | |
| CHEMBL3329556 | — | IC50 | - | — | - | |
| CHEMBL3329558 | — | IC50 | - | — | - | |
| CHEMBL3329547 | — | IC50 | - | — | - | |
| CHEMBL17289 | CHS-828 | IC50 | - | — | - |