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Assay Detail

CHEMBL3363335

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Binding
Binding affinity to serine recemase (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Serine racemase (CHEMBL4460)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

In silico and pharmacological screenings identify novel serine racemase inhibitors.
Mori H, Wada R, Li J, Ishimoto T, Mizuguchi M, Obita T, Gouda H, Hirono S, Toyooka N.
Bioorg Med Chem Lett (2014) 24 : 3732 -3735
PubMed 25066953 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 3 4.72 4.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3317781 1 4.96
CHEMBL7942 MALONIC ACID 1 4.48
CHEMBL773 GLYCINE 4.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3317781 Ki = 11000.0 nM 4.96
CHEMBL7942 MALONIC ACID Ki = 33000.0 nM 4.48
CHEMBL773 GLYCINE Ki = 366000.0 nM -