Assay Detail
Functional
CHEMBL3363816
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Antiviral activity against Norovirus infected in HG23 cells assessed as inhibition of viral-induced cytopathicity
4
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Norovirus |
| Cell Type | HG23 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
The enantiomers of the 1',6'-isomer of neplanocin A: synthesis and antiviral properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.54 | 6.11 |
| EC90 | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3334763 | — | — | 2 | 6.11 |
| CHEMBL3334764 | — | — | 2 | 4.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3334763 | — | EC50 | = | 784.0 | nM | 6.11 |
| CHEMBL3334764 | — | EC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL3334763 | — | EC90 | = | 8.884 | uM | - |
| CHEMBL3334764 | — | EC90 | = | 89.0 | uM | - |