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Assay Detail

CHEMBL3364163

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of acetylcholine esterase (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Acetylcholinesterase (CHEMBL220)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Biased and unbiased strategies to identify biologically active small molecules.
Abet V, Mariani A, Truscott FR, Britton S, Rodriguez R.
Bioorg Med Chem (2014) 22 : 4474 -4489
PubMed 24811300 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.32 8.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3313966 1 8.64
CHEMBL1134 DECAMETHONIUM BROMIDE 4.0 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3313966 IC50 = 2.3 nM 8.64
CHEMBL1134 DECAMETHONIUM BROMIDE IC50 = 1000.0 nM 6.00