Assay Detail
Functional
CHEMBL3364237
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Influenza A virus A/Virginia/ATCC3/2009 infected in MDCK cells assessed as reduction in host cell viability after 72 hrs by MTS assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Influenza A virus |
| Cell Type | MDCK |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Semisynthetic teicoplanin derivatives as new influenza virus binding inhibitors: synthesis and antiviral studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 8 | 5.18 | 5.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3310643 | — | — | 1 | 5.89 |
| CHEMBL1643 | RIBAVIRIN | 4.0 | 1 | 4.96 |
| CHEMBL222813 | ZANAMIVIR | 4.0 | 1 | 4.70 |
| CHEMBL3310642 | — | — | 1 | - |
| CHEMBL3310644 | — | — | 1 | - |
| CHEMBL3310645 | — | — | 1 | - |
| CHEMBL660 | AMANTADINE | 4.0 | 1 | - |
| CHEMBL959 | RIMANTADINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3310643 | — | EC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL1643 | RIBAVIRIN | EC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL222813 | ZANAMIVIR | EC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL3310642 | — | EC50 | < | 800.0 | nM | - |
| CHEMBL3310644 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL3310645 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL660 | AMANTADINE | EC50 | > | 500000.0 | nM | - |
| CHEMBL959 | RIMANTADINE | EC50 | > | 500000.0 | nM | - |