Assay Detail
Functional
CHEMBL3364567
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Antiviral activity against Influenza B virus (B/HK/05/1972) infected in MDCK cells assessed as reduction in host cell viability after 72 hrs by MTS assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Influenza B virus |
| Cell Type | MDCK |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Semisynthetic teicoplanin derivatives as new influenza virus binding inhibitors: synthesis and antiviral studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 8 | 5.31 | 5.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3310642 | — | — | 1 | 5.82 |
| CHEMBL1643 | RIBAVIRIN | 4.0 | 1 | 5.09 |
| CHEMBL222813 | ZANAMIVIR | 4.0 | 1 | 5.03 |
| CHEMBL3310643 | — | — | 1 | - |
| CHEMBL3310644 | — | — | 1 | - |
| CHEMBL3310645 | — | — | 1 | - |
| CHEMBL660 | AMANTADINE | 4.0 | 1 | - |
| CHEMBL959 | RIMANTADINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3310642 | — | EC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL1643 | RIBAVIRIN | EC50 | = | 8200.0 | nM | 5.09 |
| CHEMBL222813 | ZANAMIVIR | EC50 | = | 9400.0 | nM | 5.03 |
| CHEMBL3310643 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL3310644 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL3310645 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL660 | AMANTADINE | EC50 | > | 500000.0 | nM | - |
| CHEMBL959 | RIMANTADINE | EC50 | > | 500000.0 | nM | - |