Assay Detail
Functional
CHEMBL3365529
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Cytotoxicity against rat C6 cells assessed as cell viability after 72 hrs by CCK cell proliferation assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Cell Type | C6 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Total syntheses of parthenolide and its analogues with macrocyclic stereocontrol.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.90 | 5.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL477923 | — | — | 1 | 5.41 |
| CHEMBL4298697 | — | — | 1 | 5.18 |
| CHEMBL3322515 | — | — | 1 | 4.62 |
| CHEMBL3322516 | — | — | 1 | 4.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL477923 | — | IC50 | = | 3900.0 | nM | 5.41 |
| CHEMBL4298697 | — | IC50 | = | 6600.0 | nM | 5.18 |
| CHEMBL3322515 | — | IC50 | = | 24000.0 | nM | 4.62 |
| CHEMBL3322516 | — | IC50 | = | 41800.0 | nM | 4.38 |