Assay Detail
Functional
CHEMBL3365612
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against mouse ID8 cells overexpressing biotin receptor assessed as growth inhibition treated for 24 hrs then incubated 48 hrs with camptothecin by MTT assay in presence of camptothecin
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | ID8 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, synthesis, and biological evaluations of tumor-targeting dual-warhead conjugates for a taxoid-camptothecin combination chemotherapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.02 | 9.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3298846 | — | — | 1 | 9.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3298846 | — | IC50 | = | 0.96 | nM | 9.02 |