Assay Detail
Binding
CHEMBL3366401
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Inhibition of Candida albicans ATCC 10231 isocitrate lyase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Candida albicans |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Bahamaolide A from the marine-derived Streptomyces sp. CNQ343 inhibits isocitrate lyase in Candida albicans.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.85 | 4.93 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2047351 | BAHAMAOLIDE A | — | 1 | 4.93 |
| CHEMBL451226 | — | — | 1 | 4.76 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2047351 | BAHAMAOLIDE A | IC50 | = | 11820.0 | nM | 4.93 |
| CHEMBL451226 | — | IC50 | = | 17270.0 | nM | 4.76 |