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Assay Detail

CHEMBL3366674

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of influenza A virus wild type M2 proton channel expressed in Xenopus oocytes by two-electrode voltage clamp analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Influenza A virus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Matrix protein 2 (CHEMBL1932894)
Type SINGLE PROTEIN
Organism Influenza A virus

Publication

Azapropellanes with anti-influenza a virus activity.
Torres E, Leiva R, Gazzarrini S, Rey-Carrizo M, Frigolé-Vivas M, Moroni A, Naesens L, Vázquez S.
ACS Med Chem Lett (2014) 5 : 831 -836
PubMed 25050174 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.47 4.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1789779 1 4.47

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1789779 IC50 = 33500.0 nM 4.47