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Assay Detail

CHEMBL3367445

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Mixed-type inhibition of bovine xanthine oxidase assessed as inhibition of uric acid formation by Lineweaver-Burk plot
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bos taurus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Xanthine dehydrogenase/oxidase (CHEMBL3649)
Type SINGLE PROTEIN
Organism Bos taurus

Publication

Synthesis and bioevaluation of 2-phenyl-4-methyl-1,3-selenazole-5-carboxylic acids as potent xanthine oxidase inhibitors.
Guan Q, Cheng Z, Ma X, Wang L, Feng D, Cui Y, Bao K, Wu L, Zhang W.
Eur J Med Chem (2014) 85 : 508 -516
PubMed 25113879 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.05 9.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3331617 1 9.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3331617 Ki = 0.9 nM 9.05