Assay Detail
Binding
CHEMBL3368778
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Antagonist activity at alpha5beta1 integrin receptor (unknown origin) by cell-based ELISA
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Strategies to inhibit tumor associated integrin receptors: rationale for dual and multi-antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.02 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1180976 | — | — | 1 | 7.70 |
| CHEMBL1180969 | — | — | 1 | 6.19 |
| CHEMBL3319231 | — | — | 1 | 4.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1180976 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL1180969 | — | IC50 | = | 640.0 | nM | 6.19 |
| CHEMBL3319231 | — | IC50 | = | 70000.0 | nM | 4.16 |