Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL3368779

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Antagonist activity at alphavbeta1 integrin receptor (unknown origin) by cell-based ELISA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 7 — Homologous single protein target
Curated By Autocuration

Target

Integrin alpha-V/beta-1 (CHEMBL2111407)
Type PROTEIN COMPLEX
Organism Homo sapiens

Publication

Strategies to inhibit tumor associated integrin receptors: rationale for dual and multi-antagonists.
Sheldrake HM, Patterson LH.
J Med Chem (2014) 57 : 6301 -6315
PubMed 24568695 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.50 6.50

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3319231 1 6.50

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3319231 IC50 = 317.0 nM 6.50