Assay Detail
Functional
CHEMBL3369758
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV infected in PBMC assessed as protein-adjusted compound concentration
6
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus (CHEMBL613758) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus |
Publication
Naphthyridinone (NTD) integrase inhibitors 4. Investigating N1 acetamide substituent effects with C3 amide groups.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC90 | 3 | - | - |
| IC50 | 3 | 7.91 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3310096 | — | — | 2 | 8.00 |
| CHEMBL3310087 | — | — | 2 | 7.89 |
| CHEMBL3309905 | — | — | 2 | 7.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3310096 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL3310087 | — | IC50 | = | 13.0 | nM | 7.89 |
| CHEMBL3309905 | — | IC50 | = | 14.0 | nM | 7.85 |
| CHEMBL3310096 | — | IC90 | = | 41.0 | nM | - |
| CHEMBL3310087 | — | IC90 | = | 50.0 | nM | - |
| CHEMBL3309905 | — | IC90 | = | 55.0 | nM | - |