Assay Detail
Binding
CHEMBL3370249
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Irreversible inhibition of recombinant rat FAAH preincubated for 3 hrs
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery libraries targeting the major enzyme classes: the serine hydrolases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 9 | 8.64 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3318616 | — | — | 1 | 10.00 |
| CHEMBL3318605 | — | — | 1 | 9.80 |
| CHEMBL3318607 | — | — | 1 | 9.54 |
| CHEMBL3318610 | — | — | 1 | 9.44 |
| CHEMBL3318606 | — | — | 1 | 9.33 |
| CHEMBL3318614 | — | — | 1 | 8.04 |
| CHEMBL3318603 | — | — | 1 | 8.01 |
| CHEMBL3318604 | — | — | 1 | 6.89 |
| CHEMBL3318615 | — | — | 1 | 6.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3318616 | — | Ki | = | 0.1 | nM | 10.00 |
| CHEMBL3318605 | — | Ki | = | 0.16 | nM | 9.80 |
| CHEMBL3318607 | — | Ki | = | 0.29 | nM | 9.54 |
| CHEMBL3318610 | — | Ki | = | 0.36 | nM | 9.44 |
| CHEMBL3318606 | — | Ki | = | 0.47 | nM | 9.33 |
| CHEMBL3318614 | — | Ki | = | 9.2 | nM | 8.04 |
| CHEMBL3318603 | — | Ki | = | 9.8 | nM | 8.01 |
| CHEMBL3318604 | — | Ki | = | 130.0 | nM | 6.89 |
| CHEMBL3318615 | — | Ki | = | 210.0 | nM | 6.68 |