Assay Detail

CHEMBL3370554

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Binding affinity to rhesus monkey CGRP receptor

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Macaca mulatta
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Calcitonin gene-related peptide receptor antagonists: new therapeutic agents for migraine.

Bell IM.
J Med Chem (2014) 57 : 7838 -7858
PubMed 24960305 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Ki	2	9.77	10.62

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL1910936	MK3207	2.0	1	10.62
CHEMBL236593	TELCAGEPANT	3.0	1	8.92

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL1910936	MK3207	Ki	=	0.024	nM	10.62
CHEMBL236593	TELCAGEPANT	Ki	=	1.2	nM	8.92