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Assay Detail

CHEMBL3370872

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Mixed-type inhibition of bovine xanthine oxidase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bos taurus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Xanthine dehydrogenase/oxidase (CHEMBL3649)
Type SINGLE PROTEIN
Organism Bos taurus

Publication

X-ray crystal structure of a xanthine oxidase complex with the flavonoid inhibitor quercetin.
Cao H, Pauff JM, Hille R.
J Nat Prod (2014) 77 : 1693 -1699
PubMed 25060641 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.92 9.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1164729 FEBUXOSTAT 4.0 1 9.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1164729 FEBUXOSTAT Ki = 0.12 nM 9.92