Assay Detail
Binding
CHEMBL3371206
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate preincubated for 60 mins followed by substrate addition
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification and characterization of a new reversible MAGL inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.48 | 8.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL570812 | — | — | 1 | 8.05 |
| CHEMBL3297865 | — | — | 1 | 4.91 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL570812 | — | IC50 | = | 9.0 | nM | 8.05 |
| CHEMBL3297865 | — | IC50 | = | 12200.0 | nM | 4.91 |