Assay Detail
Binding
CHEMBL3371292
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of proteasome subunit beta-5c/i in human RPMI8226 cells by fluorescent densitometry
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | RPMI-8226 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structure-based design of β1i or β5i specific inhibitors of human immunoproteasomes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.19 | 4.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3319604 | — | — | 1 | 4.19 |
| CHEMBL3319593 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3319604 | — | IC50 | = | 65000.0 | nM | 4.19 |
| CHEMBL3319593 | — | IC50 | > | 10000.0 | nM | - |