Assay Detail
Binding
CHEMBL3371695
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human LMW-PTP IF2 using p-nitrophenylphosphate as substrate by spectrophotometry
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Low molecular weight phosphotyrosine protein phosphatase (CHEMBL4903) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Synthesis of oleanolic acid derivatives: In vitro, in vivo and in silico studies for PTP-1B inhibition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.62 | 4.91 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3343062 | — | — | 1 | 4.91 |
| CHEMBL168 | OLEANOLIC_ACID | — | 1 | 4.64 |
| CHEMBL3343064 | — | — | 1 | 4.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3343062 | — | IC50 | = | 12300.0 | nM | 4.91 |
| CHEMBL168 | OLEANOLIC_ACID | IC50 | = | 22900.0 | nM | 4.64 |
| CHEMBL3343064 | — | IC50 | = | 47400.0 | nM | 4.32 |