Assay Detail
Functional
CHEMBL3372608
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of IFN-gamma/LPS-induced PGE2 production in mouse RAW264.7 cells after 17 to 20 hrs by EIA method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | RAW264.7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Inhibition of prostaglandin E(2) production by synthetic minor prenylated chalcones and flavonoids: synthesis, biological activity, crystal structure, and in silico evaluation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.34 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL7162 | NS-398 | — | 1 | 7.00 |
| CHEMBL3318159 | — | — | 1 | 5.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL7162 | NS-398 | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL3318159 | — | IC50 | = | 2100.0 | nM | 5.68 |