Assay Detail
Binding
CHEMBL3373360
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Agonist activity at rat NK3R
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Development of novel neurokinin 3 receptor (NK3R) selective agonists with resistance to proteolytic degradation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.81 | 7.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL106124 | SENKTIDE | — | 1 | 7.89 |
| CHEMBL3361404 | — | — | 1 | 7.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL106124 | SENKTIDE | EC50 | = | 13.0 | nM | 7.89 |
| CHEMBL3361404 | — | EC50 | = | 19.0 | nM | 7.72 |