Assay Detail
Functional
CHEMBL3373731
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Antiproliferative activity against IL3-dependent mouse BAF3 cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | BaF3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Pim kinase inhibitors for the treatment of cancer and possibly more.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.09 | 5.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3318853 | — | — | 1 | 5.47 |
| CHEMBL3318856 | — | — | 1 | 4.91 |
| CHEMBL3318854 | — | — | 1 | 4.90 |
| CHEMBL3318855 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3318853 | — | IC50 | = | 3400.0 | nM | 5.47 |
| CHEMBL3318856 | — | IC50 | = | 12200.0 | nM | 4.91 |
| CHEMBL3318854 | — | IC50 | = | 12700.0 | nM | 4.90 |
| CHEMBL3318855 | — | IC50 | > | 25000.0 | nM | - |