Assay Detail
Functional
CHEMBL3374060
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Antimigratory activity against human Gli4 cells on matrix containing vitronectin after 24 hrs by 2-D migration assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Gli4 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
C-glycoside mimetics inhibit glioma stem cell proliferation, migration, and invasion.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.08 | 7.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3341777 | — | — | 1 | 7.44 |
| CHEMBL3343410 | — | — | 1 | 6.71 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3341777 | — | Ki | = | 36.0 | nM | 7.44 |
| CHEMBL3343410 | — | Ki | = | 194.0 | nM | 6.71 |