Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL3374386

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human OVCAR5 cells after 48 hrs by MTT assay
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type OVCAR-5
Confidence 1 — Organism
Curated By Autocuration

Publication

An investigation of in vitro cytotoxicity and apoptotic potential of aromatic diselenides.
Rizvi MA, Guru S, Naqvi T, Kumar M, Kumbhar N, Akhoon S, Banday S, Singh SK, Bhushan S, Mustafa Peerzada G, Shah BA.
Bioorg Med Chem Lett (2014) 24 : 3440 -3446
PubMed 24961641 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 13 4.57 4.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3314697 1 4.80
CHEMBL3314693 1 4.70
CHEMBL3314696 1 4.68
CHEMBL3314695 1 4.62
CHEMBL3314698 1 4.60
CHEMBL2409555 1 4.58
CHEMBL3314689 1 4.57
CHEMBL3314694 1 4.57
CHEMBL2002452 1 4.51
CHEMBL3314692 1 4.47
CHEMBL3122204 1 4.42
CHEMBL3314690 1 4.42
CHEMBL3314691 1 4.41

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3314697 IC50 = 16000.0 nM 4.80
CHEMBL3314693 IC50 = 20000.0 nM 4.70
CHEMBL3314696 IC50 = 21000.0 nM 4.68
CHEMBL3314695 IC50 = 24000.0 nM 4.62
CHEMBL3314698 IC50 = 25000.0 nM 4.60
CHEMBL2409555 IC50 = 26000.0 nM 4.58
CHEMBL3314689 IC50 = 27000.0 nM 4.57
CHEMBL3314694 IC50 = 27000.0 nM 4.57
CHEMBL2002452 IC50 = 31000.0 nM 4.51
CHEMBL3314692 IC50 = 34000.0 nM 4.47
CHEMBL3122204 IC50 = 38000.0 nM 4.42
CHEMBL3314690 IC50 = 38000.0 nM 4.42
CHEMBL3314691 IC50 = 39000.0 nM 4.41