Assay Detail
Binding
CHEMBL3375249
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human BChE at 50 nM by stopped flow apparatus method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.07 | 8.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3338394 | — | — | 1 | 8.57 |
| CHEMBL3338395 | — | — | 1 | 7.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3338394 | — | Ki | = | 2.71 | nM | 8.57 |
| CHEMBL3338395 | — | Ki | = | 27.05 | nM | 7.57 |