Assay Detail
Functional
CHEMBL3375681
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Cytotoxicity against human PANC1 cells after 72 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PANC-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Phorbaketals L-N, cytotoxic sesterterpenoids isolated from the marine sponge of the genus Phorbas.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.60 | 4.94 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3322969 | — | — | 1 | 4.94 |
| CHEMBL3322970 | — | — | 1 | 4.87 |
| CHEMBL3322967 | — | — | 1 | 4.30 |
| CHEMBL185 | FLUOROURACIL | 4.0 | 1 | 4.30 |
| CHEMBL3322968 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3322969 | — | IC50 | = | 11400.0 | nM | 4.94 |
| CHEMBL3322970 | — | IC50 | = | 13500.0 | nM | 4.87 |
| CHEMBL3322967 | — | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL185 | FLUOROURACIL | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL3322968 | — | IC50 | > | 50000.0 | nM | - |