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Assay Detail

CHEMBL3377306

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of CDC25B (unknown origin) using pNPP as substrate by spectrophotometry
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

M-phase inducer phosphatase 2 (CHEMBL4804)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Bioactive constituents from the green alga Caulerpa racemosa.
Yang P, Liu DQ, Liang TJ, Li J, Zhang HY, Liu AH, Guo YW, Mao SC.
Bioorg Med Chem (2015) 23 : 38 -45
PubMed 25497963 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.00 6.01

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL168 OLEANOLIC_ACID 1 6.01
CHEMBL1223852 1 4.63
CHEMBL3356396 1 4.37

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL168 OLEANOLIC_ACID IC50 = 980.0 nM 6.01
CHEMBL1223852 IC50 = 23230.0 nM 4.63
CHEMBL3356396 IC50 = 42920.0 nM 4.37