Assay Detail
ADMET
CHEMBL3377829
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Cytotoxicity against african green monkey Vero cells after 72 hrs
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Chlorocebus sabaeus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Prospects of an alternative treatment against Trypanosoma cruzi based on abietic acid derivatives show promising results in Balb/c mouse model.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.45 | 4.87 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL110 | BENZNIDAZOLE | 4.0 | 1 | 4.87 |
| CHEMBL195296 | SUGIOL | — | 1 | 4.34 |
| CHEMBL3355356 | — | — | 1 | 4.14 |
| CHEMBL3355358 | — | — | 1 | - |
| CHEMBL3355357 | — | — | 1 | - |
| CHEMBL3355355 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL110 | BENZNIDAZOLE | IC50 | = | 13600.0 | nM | 4.87 |
| CHEMBL195296 | SUGIOL | IC50 | = | 45400.0 | nM | 4.34 |
| CHEMBL3355356 | — | IC50 | = | 72700.0 | nM | 4.14 |
| CHEMBL3355358 | — | IC50 | = | 473600.0 | nM | - |
| CHEMBL3355357 | — | IC50 | = | 221600.0 | nM | - |
| CHEMBL3355355 | — | IC50 | = | 183600.0 | nM | - |