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Assay Detail

CHEMBL3377970

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Binding
Inhibition of BLM helicase (unknown origin) assessed as branch migration activity
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

RecQ-like DNA helicase BLM (CHEMBL1293237)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Targeting the homologous recombination pathway by small molecule modulators.
Huang F, Mazin AV.
Bioorg Med Chem Lett (2014) 24 : 3006 -3013
PubMed 24856061 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.30 4.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2426168 1 4.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2426168 IC50 = 50000.0 nM 4.30