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Assay Detail

CHEMBL3378403

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human recombinant FAAH using AMC arachidonoyl amide as substrate by fluorescence assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Fatty-acid amide hydrolase 1 (CHEMBL2243)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Inhibition of FAAH, TRPV1, and COX2 by NSAID-serotonin conjugates.
Rose TM, Reilly CA, Deering-Rice CE, Brewster C, Brewster C.
Bioorg Med Chem Lett (2014) 24 : 5695 -5698
PubMed 25467164 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.97 5.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3359452 1 5.30
CHEMBL3359453 1 4.82
CHEMBL191534 1 4.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3359452 IC50 = 5000.0 nM 5.30
CHEMBL3359453 IC50 = 15000.0 nM 4.82
CHEMBL191534 IC50 = 16000.0 nM 4.80