Assay Detail
Binding
CHEMBL3379235
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]-deltorphine from human delta opioid receptor expressed in CHO-K1 cells by scintillation counting analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO-K1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and pharmacological evaluation of 5-pyrrolidinylquinoxalines as a novel class of peripherally restricted κ-opioid receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.09 | 8.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL13470 | SNC-80 | — | 1 | 8.92 |
| CHEMBL80 | NALOXONE | 4.0 | 1 | 6.99 |
| CHEMBL3323515 | — | — | 1 | 5.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL13470 | SNC-80 | Ki | = | 1.2 | nM | 8.92 |
| CHEMBL80 | NALOXONE | Ki | = | 103.0 | nM | 6.99 |
| CHEMBL3323515 | — | Ki | = | 4300.0 | nM | 5.37 |