Assay Detail
Functional
CHEMBL3379346
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Inhibition of lipid peroxidation in rat liver microsomes
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Liver |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Inhibitory effects of p-alkylaminophenol on melanogenesis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.96 | 7.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3330295 | — | — | 1 | 7.85 |
| CHEMBL427462 | — | — | 1 | 7.82 |
| CHEMBL376316 | — | — | 1 | 7.81 |
| CHEMBL3330296 | — | — | 1 | 7.48 |
| CHEMBL38 | TRETINOIN | 4.0 | 1 | 5.50 |
| CHEMBL7301 | FENRETINIDE | 3.0 | 1 | 5.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3330295 | — | IC50 | = | 14.0 | nM | 7.85 |
| CHEMBL427462 | — | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL376316 | — | IC50 | = | 15.5 | nM | 7.81 |
| CHEMBL3330296 | — | IC50 | = | 33.0 | nM | 7.48 |
| CHEMBL38 | TRETINOIN | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL7301 | FENRETINIDE | IC50 | = | 5000.0 | nM | 5.30 |