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Assay Detail

CHEMBL3379660

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against Sf9 cells after 48 hrs by WST-8 assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Spodoptera frugiperda
Cell Type Sf9
Confidence 1 — Organism
Curated By Autocuration

Publication

Revised stereochemistry of ficifolidione and its biological activities against insects and cells.
Nishiwaki H, Fujiwara S, Wukirsari T, Iwamoto H, Mori S, Nishi K, Sugahara T, Yamauchi S, Shuto Y.
J Nat Prod (2015) 78 : 43 -49
PubMed 25495518 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 4.30 4.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3354992 1 4.52
CHEMBL3354990 1 4.49
CHEMBL3354991 1 4.20
CHEMBL3354993 1 4.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3354992 IC50 = 30110.0 nM 4.52
CHEMBL3354990 IC50 = 32140.0 nM 4.49
CHEMBL3354991 IC50 = 63540.0 nM 4.20
CHEMBL3354993 IC50 = 99170.0 nM 4.00