Assay Detail
Functional
CHEMBL3380242
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Cytotoxicity against human SNU182 cells after 72 hrs by SRB assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SNU-182 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis of novel substituted purine derivatives and identification of the cell death mechanism.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.79 | 5.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3355813 | — | — | 1 | 5.08 |
| CHEMBL3355820 | — | — | 1 | 5.02 |
| CHEMBL3355391 | — | — | 1 | 4.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3355813 | — | IC50 | = | 8400.0 | nM | 5.08 |
| CHEMBL3355820 | — | IC50 | = | 9600.0 | nM | 5.02 |
| CHEMBL3355391 | — | IC50 | = | 55400.0 | nM | 4.26 |