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Assay Detail

CHEMBL3380902

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human FOCUS cells after 24 hrs by SRB assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type FOCUS
Confidence 1 — Organism
Curated By Autocuration

Publication

Synthesis of novel substituted purine derivatives and identification of the cell death mechanism.
Demir Z, Guven EB, Ozbey S, Kazak C, Atalay RC, Tuncbilek M.
Eur J Med Chem (2015) 89 : 701 -720
PubMed 25462277 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.78 4.78

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3355820 1 4.78

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3355820 IC50 = 16700.0 nM 4.78