Assay Detail
Binding
CHEMBL3383000
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Binding affinity to porcine tubulin incubated for 1 hr by spectrofluorometry
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Development of a new benzophenone-diketopiperazine-type potent antimicrotubule agent possessing a 2-pyridine structure.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 5.95 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1096380 | PLINABULIN | 3.0 | 1 | 6.00 |
| CHEMBL3342339 | — | — | 1 | 5.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1096380 | PLINABULIN | Kd | = | 1000.0 | nM | 6.00 |
| CHEMBL3342339 | — | Kd | = | 1300.0 | nM | 5.89 |