Assay Detail
ADMET
CHEMBL3383775
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Cytotoxicity against rat L6 cells after 6 days by resazurin assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Rattus norvegicus |
| Cell Type | L6 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and antiprotozoal activity of oligomethylene- and p-phenylene-bis(methylene)-linked bis(+)-huprines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.11 | 5.79 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3353039 | — | — | 1 | 5.79 |
| CHEMBL3353040 | — | — | 1 | 5.31 |
| CHEMBL3353041 | — | — | 1 | 5.11 |
| CHEMBL140476 | HUPRINE Y | — | 1 | 5.11 |
| CHEMBL3353043 | — | — | 1 | 4.79 |
| CHEMBL3353042 | — | — | 1 | 4.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3353039 | — | IC50 | = | 1610.0 | nM | 5.79 |
| CHEMBL3353040 | — | IC50 | = | 4920.0 | nM | 5.31 |
| CHEMBL3353041 | — | IC50 | = | 7710.0 | nM | 5.11 |
| CHEMBL140476 | HUPRINE Y | IC50 | = | 7800.0 | nM | 5.11 |
| CHEMBL3353043 | — | IC50 | = | 16100.0 | nM | 4.79 |
| CHEMBL3353042 | — | IC50 | = | 28500.0 | nM | 4.54 |