Assay Detail
Functional
CHEMBL3384587
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Antiviral activity against Dengue virus assessed as inhibition of viral replication
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Dengue virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A perspective on targeting non-structural proteins to combat neglected tropical diseases: Dengue, West Nile and Chikungunya viruses.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.77 | 5.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL226335 | RUTIN | 3.0 | 1 | 5.77 |
| CHEMBL3344315 | — | — | 1 | 5.77 |
| CHEMBL402947 | SPIRAEOSIDE | — | 1 | 5.77 |
| CHEMBL269277 | BETULINIC ACID | 1.0 | 1 | 5.77 |
| CHEMBL251254 | HYPEROSIDE | — | 1 | 5.77 |
| CHEMBL82242 | QUERCITRIN | — | 1 | 5.77 |
| CHEMBL471282 | AVICULARIN | — | 1 | 5.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL226335 | RUTIN | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL3344315 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL402947 | SPIRAEOSIDE | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL269277 | BETULINIC ACID | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL251254 | HYPEROSIDE | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL82242 | QUERCITRIN | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL471282 | AVICULARIN | IC50 | = | 1700.0 | nM | 5.77 |