Assay Detail
Binding
CHEMBL3384589
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Non-competitive inhibition of West Nile virus NS2B-NS3 protease
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | West Nile virus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A perspective on targeting non-structural proteins to combat neglected tropical diseases: Dengue, West Nile and Chikungunya viruses.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.98 | 5.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3344319 | — | — | 1 | 5.66 |
| CHEMBL3344318 | — | — | 1 | 5.27 |
| CHEMBL206106 | PALMITINE | — | 1 | 4.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3344319 | — | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL3344318 | — | IC50 | = | 5410.0 | nM | 5.27 |
| CHEMBL206106 | PALMITINE | IC50 | = | 96000.0 | nM | 4.02 |