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Assay Detail

CHEMBL3385789

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Physicochemical
Antioxidant activity assessed as DPPH radical scavenging activity after 10 mins
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Physicochemical
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

New silibinin glyco-conjugates: synthesis and evaluation of antioxidant properties.
Zarrelli A, Romanucci V, Tuccillo C, Federico A, Loguercio C, Gravante R, Di Fabio G.
Bioorg Med Chem Lett (2014) 24 : 5147 -5149
PubMed 25442301 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 7 5.54 6.51

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL50 QUERCETIN 3.0 1 6.51
CHEMBL315670 1 4.57
CHEMBL9509 SILIBININ 3.0 1 -
CHEMBL3338306 1 -
CHEMBL3338305 1 -
CHEMBL3338304 1 -
CHEMBL3338303 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL50 QUERCETIN IC50 = 310.0 nM 6.51
CHEMBL315670 IC50 = 27000.0 nM 4.57
CHEMBL9509 SILIBININ IC50 = 392200.0 nM -
CHEMBL3338306 IC50 = 154700.0 nM -
CHEMBL3338305 IC50 = 233000.0 nM -
CHEMBL3338304 IC50 = 108000.0 nM -
CHEMBL3338303 IC50 = 301700.0 nM -