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Assay Detail

CHEMBL3387002

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Functional
Antiproliferative activity against human MGC803 cells by MTT assay
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MGC-803
Confidence 1 — Organism
Curated By Autocuration

Target

MGC-803 (CHEMBL3706566)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis and antiproliferative evaluation of 2-hydroxylated (E)-stilbenes.
Zhang Y, Shen M, Cui S, Hou T.
Bioorg Med Chem Lett (2014) 24 : 5470 -5472
PubMed 25455486 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 12 5.50 7.46

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL507494 1 7.46
CHEMBL43395 1 6.10
CHEMBL1668711 1 5.96
CHEMBL3354301 1 5.51
CHEMBL3354309 1 5.48
CHEMBL3354307 1 5.46
CHEMBL3354310 1 5.35
CHEMBL3354308 1 5.30
CHEMBL206049 1 5.20
CHEMBL3354311 1 4.97
CHEMBL3354312 1 4.83
CHEMBL165 RESVERATROL 3.0 1 4.38

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL507494 IC50 = 35.0 nM 7.46
CHEMBL43395 IC50 = 800.0 nM 6.10
CHEMBL1668711 IC50 = 1100.0 nM 5.96
CHEMBL3354301 IC50 = 3100.0 nM 5.51
CHEMBL3354309 IC50 = 3300.0 nM 5.48
CHEMBL3354307 IC50 = 3500.0 nM 5.46
CHEMBL3354310 IC50 = 4500.0 nM 5.35
CHEMBL3354308 IC50 = 5000.0 nM 5.30
CHEMBL206049 IC50 = 6300.0 nM 5.20
CHEMBL3354311 IC50 = 10600.0 nM 4.97
CHEMBL3354312 IC50 = 14700.0 nM 4.83
CHEMBL165 RESVERATROL IC50 = 42000.0 nM 4.38