Compound Detail
CHEMBL3354301
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Basic Information
| ChEMBL ID | CHEMBL3354301 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JAZINRRGQANIMG-MDZDMXLPSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
221.3
MW (Da)
3.43
ALogP
2
HBA
1
HBD
44.0
PSA (Ų)
0.79
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.51
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| MGC-803 CHEMBL3706566 | IC50 | 5.51 | 5.51 | 3100.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| MGC-803 | IC50 | = | 3100.0 | nM | 5.51 | Antiproliferative activity against human MGC803 cells by MTT assay | 25455486 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 25455486 | 10.1016/j.bmcl.2014.10.009 | MGC-803 | 1 |
Data from ChEMBL 36 via Core Engine